By Rut Gómez de Segura (Gynaecologist – Reg. No. 28/2908776). Article updated and medically reviewed on 28/10/2026 by Manuel Izquierdo (Licensed Gynecologist – 280308601).
At IVF-Life, we’re aware that during your fertility treatment you may have many queries, about symptoms, procedures and especially about medication.
As fertility specialists, we’re here to help you and be your greatest support, that’s why in this feature we’re offering you a practical guide. Using text and videos we explain how the medication works and how the drugs responsible for making your journey to motherhood possible should be administered, always under the premise that this is a safe and controlled process.
Medication plays an important role in assisted reproduction, particularly during ovarian stimulation. Understanding the different stages and the duration of an IVF treatment can help you better understand when each medication is administered and how the treatment process is organised.
We want you to feel safe and comfortable when you administer the medication, so we have prepared this content to explain in a very simple and understandable way how to do it comfortably at home. Plus, our nursing team and your Patient Care assistant will always be just a phone call away to clarify any additional questions you may have.
Before starting the administration of medication for IVF treatments, it is necessary to take a series of factors into account:
During in vitro fertilisation (IVF) treatment, following the prescribed doses and medication schedule is important for properly managing ovarian stimulation. However, unexpected situations can arise, such as forgetting an injection, administering it later than planned or being unsure whether you have used the correct dose.
If you forget a dose or make a mistake when administering your medication, the most important thing is to contact your medical team as soon as possible. You should not double your next dose or change your medication schedule without medical advice, as the instructions may vary depending on the medication and the stage of treatment. Some injections, particularly those used to trigger the final maturation of the eggs before egg retrieval, must be administered at a very specific time. Therefore, if anything goes wrong, the IVF-Life specialists can advise you on what to do to ensure your safety and the proper monitoring of your treatment.
Next, we have Puregon®, a purified form of FSH (follicle-stimulating hormone) that provides more consistent and controlled ovarian stimulation. It is used during ovarian stimulation to promote the growth and development of multiple follicles, with the aim of obtaining mature eggs for use in fertility treatment. The dose is adjusted according to each patient’s individual characteristics and response to treatment.
Orgalutran® is another important participant in this journey. The drug prevents the premature release of eggs, ensuring that they’re fully mature. By blocking the release of FSH and LH hormones, it enables greater control over the timing of ovulation.
Saizen® (somatropin) is a medication containing recombinant human growth hormone. Its use as an adjunct treatment in assisted reproduction has been investigated particularly in patients with a poor ovarian response.
Granocyte® is a medication prescribed for patients with embryo implantation failures. It’s an immunomodulatory drug that helps to control the immune system, enabling pregnancy and childbirth rates to be increased following fertility treatment.
Then there’s Prolutex ®, which is essential for preparing the lining of the uterus for implantation and for supporting the early stage of pregnancy. Prolutex® is administered subcutaneously, which may be more comfortable and easier to administer.
Finally, we present Ovitrelle®, which is used to trigger ovulation after ovarian stimulation. It’s a recombinant form of HCG that’s used to generate the LH peak that causes ovulation.
It is important to bear in mind that, after administration, the hCG hormone can remain detectable for several days and interfere with pregnancy tests, potentially leading to a false-positive result. For this reason, it is essential to take the test on the date specified by your medical team.
Decapeptyl® (triptorelin) is a medication that acts as a gonadotrophin-releasing hormone (GnRH) agonist. In assisted reproduction treatment, it may be used to control hormonal activity and prevent premature ovulation or, in certain protocols, to trigger the final maturation of the eggs before egg retrieval. Its administration and purpose depend on the stimulation protocol prescribed by the specialist.
On the other hand, Pergoveris® serves to stimulate the growth of ovarian follicles, thus facilitating the collection of mature oocytes. It contains exogenous FSH and LH to control ovarian stimulation and is adjusted according to the needs of each patient.
Meriofert® is a brilliant solution that combines the hormones FSH (follicle-stimulating hormone) and LH (luteinizing hormone) to help the ovaries produce and release eggs. This drug provides extra help to the ovaries when they need it to cause the development of several follicles and therefore eggs.
The medication used in fertility treatments is essential for achieving a successful pregnancy. This means that, before starting your treatment, we want you to clearly understand how it works and how it’s administered so you become familiar with all the drugs used and feel more confident.
We also know that along the way to achieving your baby’s arrival, a multitude of queries and uncertainties will arise, and this is where the support provided by your patient care assistant plays a vital role. This person is assigned to you by the IVF-Life specialist team and you can contact or call them at any time during the continuous opening hours at all our clinics.
Basak Ata, Ernesto Bosch, Simone Broer, Georg Griesinger, Michael Grynberg, Efstratios Kolibianakis, Michal Kunicki, Antonio La Marca, George Lainas, Nathalie Le Clef, Nathalie Massin, Nikolaos P. Polyzos, Sesh Kamal Sunkara, Tzvetelina Timeva, Mari Töyli, János Urbancsek, Frank Broekmans.
ESHRE guideline: ovarian stimulation for IVF/ICSI: an update in 2025.
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2026;
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Guía clínica de la Sociedad Europea de Reproducción Humana y Embriología sobre la estimulación ovárica en tratamientos de fecundación in vitro e ICSI:
https://pubmed.ncbi.nlm.nih.gov/41732035/
Michelle van der Linden, Karen Buckingham, Cindy Farquhar, Jan A. M. Kremer, Mostafa Metwally.
Luteal phase support for assisted reproduction cycles.
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2015;
CD009154
Revisión sistemática sobre la eficacia y seguridad de los tratamientos hormonales utilizados durante la fase lútea en reproducción asistida:
https://pubmed.ncbi.nlm.nih.gov/26148507/
Akanksha Sood, Gadha Mohiyiddeen, Gaity Ahmad, Cheryl Fitzgerald, Andrew Watson, Lamiya Mohiyiddeen.
Growth hormone for in vitro fertilisation (IVF).
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2021;
CD000099
Revisión sistemática sobre la utilización de la hormona del crecimiento como tratamiento complementario durante la estimulación ovárica en fecundación in vitro:
https://pubmed.ncbi.nlm.nih.gov/34808697/
Danilo Cimadomo, María José de Los Santos, Georg Griesinger, George Lainas, Nathalie Le Clef, David J. McLernon, David Montjean, Bettina Toth, Nathalie Vermeulen, Nick Macklon.
ESHRE good practice recommendations on recurrent implantation failure.
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2023;
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Documento de recomendaciones clínicas de ESHRE sobre la evaluación y el tratamiento del fallo recurrente de implantación embrionaria:
https://pubmed.ncbi.nlm.nih.gov/37332387/
Privacy Policy
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In order to consent to our transfer from this website and the processing of your data, you should carefully read the privacy policy of the social network you wish to access:
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