Although sperm DNA fragmentation can reduce fertilisation rates and increase miscarriage risk, proper treatment and lifestyle changes can help many couples conceive.
Regular evaluations are essential to monitor sperm quality and adjust treatments as needed. In some cases, genetic counselling may also be beneficial. At IVF-Life, we offer specialised consultations to assess each case and determine the best treatment options.
A good ovarian reserve increases the likelihood of natural pregnancy. The more eggs available, the greater the chances of ovulation and fertilisation.
However, although the number of eggs is important, egg quality also declines with age. Ovarian reserve and egg quality are different concepts, and age is one of the main factors associated with egg quality.
In assisted reproduction, women with a good ovarian reserve generally respond better to treatment. They can produce more eggs during a cycle, thereby increasing the chances of success.
In addition to age, which is considered the most significant factor, ovarian reserve can be influenced by a woman’s genetic predisposition to have more or fewer eggs available.
Certain treatments, such as chemotherapy or pelvic radiotherapy, can reduce ovarian reserve. Additionally, conditions like endometriosis can negatively affect the number of eggs.
Autoimmune diseases can also impact ovarian reserve and fertility. Some autoimmune conditions can attack the ovaries, reducing ovarian reserve and potentially affecting egg quality. This can make conception more difficult and increase the risk of miscarriage.
Although hysteroscopy is generally safe, like any medical procedure, it carries some risks and complications, such as allergic reactions to anaesthesia or medication used during the procedure, or infections in the uterus or fallopian tubes after the procedure.
There is also a small risk of damaging nearby organs, such as the bladder or bowel, although these risks are uncommon.
Endometrial biopsy is a procedure that is generally safe, but like any medical intervention, it carries some risks, such as slight bleeding after the procedure or a uterine infection, although this is very rare. Some women may also experience mild cramping or abdominal pain after the biopsy.
Regarding contraindications, an endometrial biopsy should not be performed on pregnant women or if there is an active pelvic infection.
If the procedure is surgical, it will be performed under general anaesthesia, so patients will not feel any pain during the procedure, although they may experience some postoperative discomfort, which can be managed with painkillers.
Spanish legislation on assisted reproduction requires assisted reproduction centres to assess egg donors for genetic, hereditary and infectious conditions that could be transmitted to their offspring.
Screening may include genetic conditions that are more prevalent in certain populations, such as Fragile X syndrome, cystic fibrosis and thalassaemia.
However, limited screening may not identify other genetic conditions that could affect the health of the future child. For this reason, IVF-Life goes a step further by performing genetic compatibility testing on its egg donors, with the aim of reducing genetic risks for patients and future children.