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Asherman’s syndrome: a condition that affects female fertility

Home > Blog > Pathologies

By Dr. José Manuel Gómez Santana (Gynecologist – License No. 030309086).

Paciente con síndrome de Asherman en consulta de IVF-Life

What is Asherman’s syndrome?

It is not one of the most well-known gynecological problems, but it is increasingly becoming a concern in women’s reproductive health. Asherman’s syndrome is a uterine condition that can cause a partial or total reduction of the uterine cavity, which may lead to difficulties in achieving pregnancy.

Although it is a rare disorder, awareness of its existence is crucial for early diagnosis and appropriate management. Detecting it in time not only improves the chances of pregnancy but also helps preserve uterine health over the long term.

The condition is named after gynecologist Josef Asherman, who first described it in 1948. It is primarily characterized by the presence of adhesions or scar tissue within the uterine cavity, which causes a partial or total reduction of the uterine space. The issue with this condition is that it often goes unnoticed for years and is only discovered when a woman tries to conceive and encounters difficulties doing so.

Infografía sobre el síndrome de Asherman

Causes of Asherman's syndrome

Among the most common causes of Asherman’s syndrome are:


These procedures can damage or destroy the basal layer of the endometrium, promoting the formation of intrauterine adhesions. These adhesions—also known as synechiae—can alter the uterine cavity, hinder embryo implantation, and cause menstrual or fertility problems.

Symptoms and warning signs

As mentioned before, many women live with this syndrome without being aware of it, since its symptoms are not always noticeable or alarming, which reduces medical follow-up and care.

The most common symptoms include decreased or absent menstrual bleeding—known as hypomenorrhea or secondary amenorrhea—or recurrent pelvic pain. However, in many women, the syndrome does not produce any obvious signs and is only detected during fertility assessments due to difficulty conceiving.

Diagnosis and treatment

Diagnosis of Asherman’s syndrome requires a hysteroscopy—a procedure that allows direct visualization of the uterine cavity to assess the extent of the adhesions.

Hysteroscopy performed on a patient with Asherman syndrome


Treatment focuses on removing the adhesions that form within the uterus to restore normal endometrial function. This improves both menstruation and fertility. The procedure is typically performed through hysteroscopic surgery, which is considered the treatment of choice. Additionally, after surgery, special intrauterine devices (IUDs) or small Foley catheters may be placed to keep the uterine walls separated during healing. Estrogens are usually administered, followed by progestogens, to stimulate endometrial regeneration and promote proper healing.

Is pregnancy possible with Asherman’s syndrome?

Many women diagnosed with this condition wish to become pregnant, but whether this is possible depends on the degree of severity. In mild cases, restoration of the uterine cavity can allow fertility to return and successful pregnancies to occur. However, when adhesions are more severe, the probability of conception decreases, and assisted reproductive techniques may be necessary.

Each patient’s condition must be carefully evaluated, but the truth is that thanks to medical advances, more and more women with Asherman’s syndrome are achieving pregnancy. Although it is a rare disorder, raising awareness about it remains essential for early diagnosis and appropriate management. Detecting it in time not only improves the chances of conception but also contributes to preserving uterine health in the long term. 

Authors

Authors and medical review

Author
Dr. José Manuel Gómez Santana

Dr José Manuel Gómez Santana is the Medical Director of IVF-Life Alicante and a Consultant Gynaecologist specialising in assisted reproduction and reproductive medicine, with more than 20 years of experience in the diagnosis and treatment of infertility. His clinical practice focuses on in vitro fertilisation (IVF), complex fertility cases and fertility preservation. He is a member of the Spanish Fertility Society (SEF), the Spanish Society of Gynaecology and Obstetrics (SEGO), the European Society of Human Reproduction and Embryology (ESHRE), and the European Society for Gynaecological Endoscopy (ESGE).

Medical review
Dr. Alejandro Olloqui Escalona

Dr. Alejandro Olloqui Escalona is a gynecologist specializing in assisted reproduction and reproductive medicine at IVF-Life Madrid. His clinical practice focuses on in vitro fertilization (IVF), complex fertility cases, and minimally invasive gynecological surgery. He is also involved in clinical practice, teaching, and research at Hospital Universitario 12 de Octubre in Madrid and actively participates in scientific activities associated with SEGO and ESGE.

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