Uterine rejuvenation

Endometrial regenerative therapy with PRP

Endometrial regenerative therapy, also known as endometrial rejuvenation, consists of reprogramming dysfunctional subendometrial tissue or damaged endometrium.

After obtaining PRP, extracted from a sample of the patient’s blood, and injecting this sort of “self-medication” directly into the uterus, tissue regeneration occurs, necessary for successful embryo implantation.

What is PRP?

Platelet-rich plasma (PRP) is a regenerative therapeutic practice through which tissue repair, reprogramming and rejuvenation are achieved. When applied to reproductive medicine, PRP offers significant benefits and has no side effects, as it is administered as self-medication through centrifugation of the patient’s blood.

Using a meticulous process, plasma with a high concentration of platelets and other plasma agents rich in Growth Factors (GFs) is separated from the blood. When these GFs are released and activated, they are injected into the uterus using various instillation techniques.

Thanks to the endocrine and paracrine effects, an efficient regeneration and repair of the subendometrial tissue are achieved, without provoking an inflammatory response. As a result, a healthier and reconstituted endometrium is preserved for several months.

Uterine rejuvenation step by step

Step 1: Taking blood from the patient.

Step 2: Separation of platelets and selection by centrifugation.

Step 3: Release of growth factors (GF).

Step 4: Two applications according to individual assessment.

  1. Intrauterine PRP instillation
  2. Subendometrial injection of PRP
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Applications of regenerative endometrial therapy.

Adenomyosis / Internal endometriosis.

Chronic endometritis / Pathological microbiome.

Hypotrophic or refractory endometrium

Asherman's syndrome.

Low subendometrial vascularization flow index (VFI).

KIR-HLAC incompatibility.

Repeated miscarriages (immunological/rheological or idiopathic).

Implantation failures (immunological/rheological or idiopathic).

Obstetric risks due to various placental pathologies (accreta, increta, pre-eclampsia and others).

*The feasibility of treatment depends on the medical diagnosis.

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