The passage of time, and everything it entails, especially affects fertility and specifically female fertility. However, thanks to science and reproductive medicine, there are increasingly more possibilities for those couples who, for various reasons, find difficulties in conceiving. Currently, there are treatments based on regenerative medicine that allow many women to reactivate the correct functioning of their reproductive organs and tissues, such as what is known as ovarian and uterine rejuvenation.
For this reason, in IVF-Life, we bring you in this article some of the most outstanding keys of these techniques that are gradually gaining ground in the world of fertility.
Awakening fertility: origins and evolution of rejuvenation techniques
Uterine and ovarian rejuvenation techniques have evolved considerably in recent years. In 2013, the first attempt to reactivate inactive follicles in patients with premature ovarian failure or low ovarian reserve took place, a process that was carried out by fragmenting ovarian cortex samples and subsequent autotransplantation.
On the other hand, uterine rejuvenation began its development in 2015, when the first clinical study was published that evaluated the administration of Platelet-Rich Plasma (PRP) intraendometrial in patients with an endometrial development below the recommended. Since then, the techniques for preparing PRP, the methods of administration, the indications, and the consistency of the results obtained have evolved to the point of gradually settling in the field of fertility.
At IVF-Life Group, we are pioneers in these techniques and we have some of the best professionals specialized in the field. The constant search for solutions to fertility problems has led us to continue investigating new techniques, such as ovarian and uterine rejuvenation, which have allowed us to reach the highest levels of excellence in our centers.
The paths of rejuvenation, techniques and procedures
There are various ovarian and uterine rejuvenation techniques but all of them are based on the use of PRP. PRP is a platelet concentrate obtained from the patient’s blood, which contains high concentrations of growth factors. These growth factors, such as Transforming Growth Factor Beta (TGF-B), Platelet-Derived Growth Factor (PDGF), and Fibroblast Growth Factor (FGF), stimulate tissue regeneration and the growth of new blood vessels, which is fundamental in assisted reproduction.
The process of obtaining PRP is quite simple: blood is drawn from the patient, it is processed in the laboratory by controlled centrifugation to then separate the plasma that contains the platelets from the rest of the blood components.
Once the PRP is obtained, it is administered to the organ to be treated, whether it is the endometrium or the ovary. For ovarian rejuvenation, small amounts of PRP are injected into the ovarian cortex through transvaginal ovarian puncture while, for uterine rejuvenation, PRP is instilled in the endometrium.
The benefits of rejuvenation: advantages and results
Ovarian and uterine rejuvenation with PRP presents several advantages compared to other techniques:
- Effectiveness: There is increasingly more data that confirm the effectiveness of these techniques in both the endometrium and ovary.
- Safety: The fact that the patient’s own PRP is used minimizes the risk of allergic reactions, infections or other complications.
- Accessibility: While these techniques are relatively new, they are increasingly integrated into the treatment flow of fertility clinics, which allows gathering more data and adjusting their use.
Among the most promising results is the improvement in endometrial quality and the reactivation of ovarian follicles, which could lead to an increase in the pregnancy rate in women with premature ovarian failure or low ovarian reserve.
The potential of stem cells in uterine and ovarian rejuvenation
Stem cells, in combination with PRP growth factors, have a significant impact on ovarian and uterine rejuvenation. These cells, together with growth factors, stimulate tissue regeneration, improve vascularization and ovarian and endometrial functionality.
The potential of stromal stem cells, especially those obtained from bone marrow and adipose tissue, lies in their ability to differentiate into different types of tissues and release growth factors that can stimulate the repair of tissues that had previously been lost.
The potential of stem cells in ovarian and uterine rejuvenation is undeniable as it has been shown to improve ovarian and endometrial functionality, key aspects that greatly aid the success of assisted reproduction treatments.
Regenerative medicine: research and perspectives
Regenerative treatments based on the use of PRP are constantly evolving and are proving to be a new hope for women and couples with difficulties conceiving. At IVF-Life Group, we continue to work and research to offer our patients the best treatment options, always based on the most recent scientific evidence.
It is important to note that, although these techniques represent hope for many women, each case is unique and must be evaluated individually. If you are interested in learning more about ovarian and uterine rejuvenation with PRP, we invite you to make a consultation with our reproductive medicine specialists. The final decision should always be made together with your doctor, taking into account your personal circumstances and the possible benefits of these procedures.
IVF-Life, seeking new paths to motherhood
Science and reproductive medicine continue to advance, offering new hopes to women who need to improve their reproductive prognosis. Innovative treatments based on stem cells and PRP growth factors represent a promising field of research, with the potential to transform reproductive medicine and offer new opportunities for uterine and ovarian rejuvenation.
It is important to remember that these treatments are still in experimental stages and more studies need to be carried out. However, advances in reproductive medicine are reasons for hope and optimism for couples looking to improve fertility and their reproductive prognosis.
To make the right decisions, it is essential that patients are well informed and fully understand the benefits associated with these treatments. The decision to carry out these procedures must be taken with the advice of a qualified health professional and with a complete understanding of the needs of each patient.
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Technology and innovation have revolutionised the field of fertility and assisted reproduction, and at IVF-Life we are at the forefront, not only in advanced treatments